Ontology highlight
ABSTRACT:
SUBMITTER: Wang LH
PROVIDER: S-EPMC5707755 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Wang Li-Hong LH Wu Min-Huan MH Chen Po-Chun PC Su Chen-Ming CM Xu Guohong G Huang Chien-Chung CC Tsai Chun-Hao CH Huang Yuan-Li YL Tang Chih-Hsin CH
International journal of medical sciences 20171102 13
Rheumatoid arthritis (RA) is a systemic inflammatory disease that causes chronic inflammation of the joints. Analysis of genetic variants offers promise for guiding treatment and improving outcomes in RA. High-mobility group box protein 1 (HMGB1) is a ubiquitous nuclear protein found in all mammal eukaryotic cells that participates in several biological functions including immune response, cell survival and apoptosis. We investigated the effects of HMGB1 gene polymorphisms on the risk of RA dise ...[more]