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The Anticancer Activities Phenolic Amides from the Stem of Lycium barbarum.


ABSTRACT: Four new phenolic amides, 4-O-methylgrossamide (1), (E)-2-(4,5-dihydroxy-2-{3-[(4-hydroxyphenethyl)amino]-3-oxopropyl}-phenyl)-3-(4-hydroxy-3-methoxyphenyl)-N-(4-hydroxyphenethyl)acryl-amide (2), (Z)-lyciumamide C (3), (Z)-thoreliamide B (4), together with thirteen known phenolic amides were identified from the stem of Lycium barbarum. The structures of the new compounds were determined by spectroscopic methods. All compounds were evaluated for their anti-cancer activities against human glioma stem cell lines.

SUBMITTER: Zhu PF 

PROVIDER: S-EPMC5709248 | biostudies-literature | 2017 Dec

REPOSITORIES: biostudies-literature

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The Anticancer Activities Phenolic Amides from the Stem of Lycium barbarum.

Zhu Pei-Feng PF   Dai Zhi Z   Wang Bei B   Wei Xin X   Yu Hao-Fei HF   Yan Zi-Ru ZR   Zhao Xu-Dong XD   Liu Ya-Ping YP   Luo Xiao-Dong XD  

Natural products and bioprospecting 20170606 6


Four new phenolic amides, 4-O-methylgrossamide (1), (E)-2-(4,5-dihydroxy-2-{3-[(4-hydroxyphenethyl)amino]-3-oxopropyl}-phenyl)-3-(4-hydroxy-3-methoxyphenyl)-N-(4-hydroxyphenethyl)acryl-amide (2), (Z)-lyciumamide C (3), (Z)-thoreliamide B (4), together with thirteen known phenolic amides were identified from the stem of Lycium barbarum. The structures of the new compounds were determined by spectroscopic methods. All compounds were evaluated for their anti-cancer activities against human glioma s  ...[more]

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