Ontology highlight
ABSTRACT:
SUBMITTER: Hermenean A
PROVIDER: S-EPMC5709492 | biostudies-literature | 2017 Nov
REPOSITORIES: biostudies-literature
Scientific reports 20171130 1
Limited self-regenerating capacity of human skeleton makes the reconstruction of critical size bone defect a significant challenge for clinical practice. Aimed for regenerating bone tissues, this study was designed to investigate osteogenic differentiation, along with bone repair capacity of 3D chitosan (CHT) scaffolds enriched with graphene oxide (GO) in critical-sized mouse calvarial defect. Histopathological/histomorphometry and scanning electron microscopy(SEM) analysis of the implants revea ...[more]