Project description:More than 40% of all deaths in children under 5 years of age occur during the neonatal period: the first month of life. Immunization of pregnant women has proven beneficial to both mother and infant by decreasing morbidity and mortality. With an increasing number of immunization trials being conducted in pregnant women, as well as roll-out of recommended vaccines to pregnant women, there is a need to clarify details of a neonatal death. This manuscript defines levels of certainty of a neonatal death, related to the viability of the neonate, who confirmed the death, and the timing of the death during the neonatal period and in relation to immunization of the mother.

| S-EPMC5139812 | biostudies-literature

Neonatal seizures: Case definition & guidelines for data collection, analysis, and presentation of immunization safety data.

Project description: Not available

| S-EPMC6899436 | biostudies-literature

Gestational diabetes mellitus: Case definition & guidelines for data collection, analysis, and presentation of immunization safety data.

Project description: Not available

| S-EPMC5710985 | biostudies-literature

Congenital anomalies: Case definition and guidelines for data collection, analysis, and presentation of immunization safety data.

Project description: Not available

| S-EPMC5139892 | biostudies-literature

Preterm birth: Case definition & guidelines for data collection, analysis, and presentation of immunisation safety data.

Project description:Preterm birth is commonly defined as any birth before 37 weeks completed weeks of gestation. An estimated 15 million infants are born preterm globally, disproportionately affecting low and middle income countries (LMIC). It contributes directly to estimated one million neonatal deaths annually and is a significant contributor to childhood morbidity. However, in many clinical settings, the information available to calculate completed weeks of gestation varies widely. Accurate dating of the last menstrual period (LMP), as well as access to clinical and ultrasonographic evaluation are important components of gestational age assessment antenatally. This case definition assign levels of confidence to categorisation of births as preterm, utilising assessment modalities which may be available across different settings. These are designed to enable systematic safety evaluation of vaccine clinical trials and post-implementation programmes of immunisations in pregnancy.

| S-EPMC5139808 | biostudies-other

Neonatal encephalopathy: Case definition & guidelines for data collection, analysis, and presentation of maternal immunisation safety data.

Project description: Not available

| S-EPMC5710979 | biostudies-literature