Ontology highlight
ABSTRACT:
SUBMITTER: Lacerda Pigosso L
PROVIDER: S-EPMC5711425 | biostudies-literature | 2017 Oct
REPOSITORIES: biostudies-literature
Lacerda Pigosso Laurine L Baeza Lilian Cristiane LC Vieira Tomazett Mariana M Batista Rodrigues Faleiro Mariana M Brianezi Dignani de Moura Veridiana Maria VM Melo Bailão Alexandre A Borges Clayton Luiz CL Alves Parente Rocha Juliana J Rocha Fernandes Gabriel G Gauthier Gregory M GM Soares Celia Maria de Almeida CMA
Virulence 20170713 7
Paracoccidoides brasiliensis and Paracoccidioides lutzii, the etiologic agents of paracoccidioidomycosis, cause disease in healthy and immunocompromised persons in Latin America. We developed a method for harvesting P. brasiliensis yeast cells from infected murine lung to facilitate in vivo transcriptional and proteomic profiling. P. brasiliensis harvested at 6 h post-infection were analyzed using RNAseq and LC-MS<sup>E</sup>. In vivo yeast cells had 594 differentially expressed transcripts and ...[more]