Ontology highlight
ABSTRACT:
SUBMITTER: Biedka S
PROVIDER: S-EPMC5711468 | biostudies-literature | 2017 Oct
REPOSITORIES: biostudies-literature
Biedka Stephanie S Wu Shan S LaPeruta Amber J AJ Gao Ning N Woolford John L JL
RNA biology 20170307 10
Ribosomes are responsible for translating the genome, in the form of mRNA, into the proteome in all organisms. Biogenesis of ribosomes in eukaryotes is a complex process involving numerous remodeling events driven in part by the concerted actions of hundreds of protein assembly factors. A major challenge in studying eukaryotic ribosome assembly has, until recently, been a lack of structural data to facilitate understanding of the conformational and compositional changes the pre-ribosome undergoe ...[more]