Ontology highlight
ABSTRACT:
SUBMITTER: van Velthoven CTJ
PROVIDER: S-EPMC5711481 | biostudies-literature | 2017 Nov
REPOSITORIES: biostudies-literature
van Velthoven Cindy T J CTJ de Morree Antoine A Egner Ingrid M IM Brett Jamie O JO Rando Thomas A TA
Cell reports 20171101 7
Muscle stem cells (MuSCs) persist in a quiescent state and activate in response to specific stimuli. The quiescent state is both actively maintained and dynamically regulated. However, analyses of quiescence have come primarily from cells removed from their niche. Although these cells are still quiescent, biochemical changes certainly occur during the isolation process. Here, we analyze the transcriptome of MuSCs in vivo utilizing MuSC-specific labeling of RNA. Notably, labeling transcripts duri ...[more]