Ontology highlight
ABSTRACT:
SUBMITTER: Shtykova EV
PROVIDER: S-EPMC5711849 | biostudies-literature | 2017 Dec
REPOSITORIES: biostudies-literature
Shtykova Eleonora V EV Dadinova Liubov A LA Fedorova Natalia V NV Golanikov Andrey E AE Bogacheva Elena N EN Ksenofontov Alexander L AL Baratova Liudmila A LA Shilova Liudmila A LA Tashkin Vsevolod Yu VY Galimzyanov Timur R TR Jeffries Cy M CM Svergun Dmitri I DI Batishchev Oleg V OV
Scientific reports 20171201 1
Influenza A virus matrix protein M1 plays an essential role in the virus lifecycle, but its functional and structural properties are not entirely defined. Here we employed small-angle X-ray scattering, atomic force microscopy and zeta-potential measurements to characterize the overall structure and association behavior of the full-length M1 at different pH conditions. We demonstrate that the protein consists of a globular N-terminal domain and a flexible C-terminal extension. The globular N-term ...[more]