Ontology highlight
ABSTRACT:
SUBMITTER: Wei B
PROVIDER: S-EPMC5715527 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
International journal of biological sciences 20171101 11
Some solid tumors are characterized by extracellular matrix (ECM) remodeling and stiffening, which is related to solid tumor progression and aggression. However, the relationship between ECM stiffness and colorectal cancer (CRC) remains unclear. In this study, we investigated the relevance of ECM stiffness to clinicopathologic features using human CRC tissue microarrays. The results demonstrate that the expression of ECM components in CRC tissues is closely correlated with CRC progression and po ...[more]