Development of an organ failure score in acute liver failure for transplant selection and identification of patients at high risk of futility.

ABSTRACT:

Introduction

King's College Hospital criteria are currently used to select liver transplant candidates in acetaminophen-related acute liver failure (ALF). Although widely accepted, they show a poor sensitivity in predicting pre-transplant mortality and cannot predict the outcome after surgery. In this study we aimed to develop a new prognostic score that can allow patient selection for liver transplantation more appropriately and identify patients at high risk of futile transplantation.

Methods

We analysed consecutive patients admitted to the Royal Free and Beaujon Hospitals between 1990 and 2015. Clinical and laboratory data at admission were collected. Predictors of 3-month mortality in the non-transplanted patients admitted to the Royal Free Hospital were used to develop

SUBMITTER: Figorilli F 

PROVIDER: S-EPMC5716582 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature