Ontology highlight
ABSTRACT:
SUBMITTER: Moine A
PROVIDER: S-EPMC5716589 | biostudies-literature | 2017 Nov
REPOSITORIES: biostudies-literature
Moine Audrey A Espinosa Leon L Martineau Eugenie E Yaikhomba Mutum M Jazleena P J PJ Byrne Deborah D Biondi Emanuele G EG Notomista Eugenio E Brilli Matteo M Molle Virginie V Gayathri Pananghat P Mignot Tâm T Mauriello Emilia M F EMF
PLoS genetics 20171121 11
The FrzCD chemoreceptor from the gliding bacterium Myxococcus xanthus forms cytoplasmic clusters that occupy a large central region of the cell body also occupied by the nucleoid. In this work, we show that FrzCD directly binds to the nucleoid with its N-terminal positively charged tail and recruits active signaling complexes at this location. The FrzCD binding to the nucleoid occur in a DNA-sequence independent manner and leads to the formation of multiple distributed clusters that explore cons ...[more]