Ontology highlight
ABSTRACT:
SUBMITTER: Ock CY
PROVIDER: S-EPMC5716702 | biostudies-literature | 2017 Nov
REPOSITORIES: biostudies-literature
Ock Chan-Young CY Kim Sehui S Keam Bhumsuk B Kim Soyeon S Ahn Yong-Oon YO Chung Eun-Jae EJ Kim Jin-Ho JH Kim Tae Min TM Kwon Seong Keun SK Jeon Yoon Kyung YK Jung Kyeong Chun KC Kim Dong-Wan DW Wu Hong-Gyun HG Sung Myung-Whun MW Heo Dae Seog DS
Oncotarget 20170616 58
Programmed death-ligand 1 (PD-L1) expression is regarded as a predictive marker for anti-PD-1/PD-L1 therapy. The purpose of study was to explore the changes in PD-L1 expression in head and neck squamous cell carcinoma (HNSCC) during treatment. Paired HNSCC tissues prior to and after cisplatin-based treatment were evaluated to determine PD-L1 protein expression by immunohistochemistry. Among the 35 HNSCC patient samples, PD-L1 expression status changed after treatment in 37.1% (13/35) of samples. ...[more]