An exploration of common dopaminergic variants and behavior problems in siblings at high risk for autism spectrum disorder.
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ABSTRACT:
SUBMITTER: Gangi DN
PROVIDER: S-EPMC5716906 | biostudies-literature | 2017 Nov
REPOSITORIES: biostudies-literature
Publications
An exploration of common dopaminergic variants and behavior problems in siblings at high risk for autism spectrum disorder.
Gangi Devon N DN Usher Lauren V LV Messinger Daniel S DS
Infant behavior & development 20171017
Younger siblings of children with ASD often exhibit elevated internalizing and externalizing problems. We investigated common dopaminergic variants (DRD4 and DRD2) in relation to behavior problems at 36 months. Genotypes linked to less efficient dopaminergic functioning were associated with higher internalizing problems in high-risk siblings. ...[more]
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