Early-Life Human Microbiota Associated With Childhood Allergy Promotes the T Helper 17 Axis in Mice.
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ABSTRACT:
SUBMITTER: Petursdottir DH
PROVIDER: S-EPMC5716970 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Publications
Early-Life Human Microbiota Associated With Childhood Allergy Promotes the T Helper 17 Axis in Mice.
Petursdottir Dagbjort H DH Nordlander Sofia S Qazi Khaleda Rahman KR Carvalho-Queiroz Claudia C Ahmed Osman Omneya O Hell Eva E Björkander Sophia S Haileselassie Yeneneh Y Navis Marit M Kokkinou Efthymia E Lio Ivan Zong Long IZL Hennemann Julia J Brodin Björn B Huseby Douglas L DL Nilsson Caroline C Hughes Diarmaid D Udekwu Klas I KI Sverremark-Ekström Eva E
Frontiers in immunology 20171201
The intestinal microbiota influences immune maturation during childhood, and is implicated in early-life allergy development. However, to directly study intestinal microbes and gut immune responses in infants is difficult. To investigate how different types of early-life gut microbiota affect immune development, we collected fecal samples from children with different allergic heredity (AH) and inoculated germ-free mice. Immune responses and microbiota composition were evaluated in the offspring ...[more]
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