ATR-FTIR spectral discrimination between normal and tumorous mouse models of lymphoma and melanoma from serum samples.
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ABSTRACT:
SUBMITTER: Ghimire H
PROVIDER: S-EPMC5717051 | biostudies-literature | 2017 Dec
REPOSITORIES: biostudies-literature
Publications
ATR-FTIR spectral discrimination between normal and tumorous mouse models of lymphoma and melanoma from serum samples.
Ghimire Hemendra H Venkataramani Mahathi M Bian Zhen Z Liu Yuan Y Perera A G Unil AGU
Scientific reports 20171205 1
This study presents, attenuated total reflection Fourier transforms infrared spectroscopy of dried serum samples in an effort to assess biochemical changes induced by non-Hodgkin's lymphoma and subcutaneous melanoma. An EL4 mouse model of non-Hodgkin lymphoma and a B16 mouse model of subcutaneous melanoma are used to extract a snapshot of tumor-associated alteration in the serum. The study of both cancer-bearing mouse models in wild types and their corresponding control types, emphasizes the dia ...[more]
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