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ABSTRACT: Background
To assess the reliability, validity, and responsiveness to treatment change of the single-item measure, Severity of Worst Tiredness, in patients with rheumatoid arthritis (RA).Methods
Data from two Phase 3, randomized, placebo-controlled (RA-BUILD; and active-controlled [RA-BEAM]), clinical studies of the efficacy of baricitinib in adults with moderately to severely active RA were used. The psychometric properties of the single-item measure, Severity of Worst Tiredness, were assessed, including test-retest reliability, convergent and discriminant validity, known-groups validity, and responsiveness, using other patient- and clinician-reported outcomes frequently assessed in RA patients.Results
Test-retest reliability of the Severity of Worst Tiredness was
SUBMITTER: Bacci ED
PROVIDER: S-EPMC5718135 | biostudies-literature | 2017 Dec
REPOSITORIES: biostudies-literature