Ontology highlight
ABSTRACT:
SUBMITTER: Wischhof L
PROVIDER: S-EPMC5719005 | biostudies-literature | 2017 Dec
REPOSITORIES: biostudies-literature
Scientific reports 20171206 1
Chromatin remodelers have emerged as prominent regulators of epigenetic processes and potential drivers of various human pathologies. The multi-subunit chromatin-remodeling SWI/SNF complex determines gene expression programs and, consequently, contributes to the differentiation, maturation and plasticity of neurons. Here, we investigate the elusive biological function of Bcl7a and Bcl7b, two newly identified subunits of the SWI/SNF complex that are highly expressed throughout the brain. We gener ...[more]