Ontology highlight
ABSTRACT:
SUBMITTER: Dragh MA
PROVIDER: S-EPMC5719063 | biostudies-literature | 2017 Dec
REPOSITORIES: biostudies-literature
Dragh Maytham A MA Xu Zhiliang Z Al-Allak Zainab S ZS Hong Ling L
Scientific reports 20171206 1
Previous studies have established the anticancer effect of vitamin K2 (VK2). However, its effect on lymphoma induced by UBIAD1/heix mutation in Drosophila remains unknown. Therefore, we aimed to develop an in vivo model of lymphoma for the precise characterization of lymphoma phenotypes. We also aimed to improve the understanding of the mechanisms that underlie the preventative effects of VK2 on lymphoma. Our results demonstrated that VK2 prevents lymphoma by acting as an electron carrier and by ...[more]