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Evaluation of melanin production by Sporothrix luriei.

ABSTRACT: There is a paucity of studies on the cell biology of Sporothrix luriei, the less common of the pathogenic Sporothrix species worldwide. The production of DHN-melanin, eumelanin, and pyomelanin were evaluated on the mycelial and yeast forms of the S. luriei ATCC 18616 strain. The mycelial form of this species produced only pyomelanin, which protected the fungus against environmental stressors such as ultraviolet light, heat, and cold. The yeast form was unable to produce any of the tested melanin types. The lack of melanin in the parasitic form of S. luriei may be an explanation for its low frequency in human infections.

SUBMITTER: Cruz ILR

PROVIDER: S-EPMC5719544 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature

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Evaluation of melanin production by Sporothrix luriei.

Cruz Ingrid Ludmilla Rodrigues ILR Figueiredo-Carvalho Maria Helena Galdino MHG Zancopé-Oliveira Rosely Maria RM Almeida-Paes Rodrigo R

Memorias do Instituto Oswaldo Cruz 20180101 1

There is a paucity of studies on the cell biology of Sporothrix luriei, the less common of the pathogenic Sporothrix species worldwide. The production of DHN-melanin, eumelanin, and pyomelanin were evaluated on the mycelial and yeast forms of the S. luriei ATCC 18616 strain. The mycelial form of this species produced only pyomelanin, which protected the fungus against environmental stressors such as ultraviolet light, heat, and cold. The yeast form was unable to produce any of the tested melanin ...[more]

PMID: 29211110

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