Ontology highlight
ABSTRACT:
SUBMITTER: Huang MF
PROVIDER: S-EPMC5722371 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Huang Ming-Fen MF Lin Shin-Jen SJ Ko Tzu-Ping TP Liao Yi-Ting YT Hsu Kai-Cheng KC Wang Hao-Ching HC
PloS one 20171208 12
DNA mimicry is a direct and effective strategy by which the mimic competes with DNA for the DNA binding sites on other proteins. Until now, only about a dozen proteins have been shown to function via this strategy, including the DNA mimic protein DMP19 from Neisseria meningitides. We have shown previously that DMP19 dimer prevents the operator DNA from binding to the transcription factor NHTF. Here, we provide new evidence that DMP19 monomer can also interact with the Neisseria nucleoid-associat ...[more]