Ontology highlight
ABSTRACT:
SUBMITTER: Schyman P
PROVIDER: S-EPMC5722789 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Schyman Patric P Liu Ruifeng R Desai Valmik V Wallqvist Anders A
Frontiers in pharmacology 20171204
In drug development, early assessments of pharmacokinetic and toxic properties are important stepping stones to avoid costly and unnecessary failures. Considerable progress has recently been made in the development of computer-based (<i>in silico</i>) models to estimate such properties. Nonetheless, such models can be further improved in terms of their ability to make predictions more rapidly, easily, and with greater reliability. To address this issue, we have used our vNN method to develop 15 ...[more]