Fibrotic Changes Mediating Acute Kidney Injury to Chronic Kidney Disease Transition.
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ABSTRACT:
SUBMITTER: O hAinmhire E
PROVIDER: S-EPMC5723252 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Publications
Fibrotic Changes Mediating Acute Kidney Injury to Chronic Kidney Disease Transition.
Ó hAinmhire Eoghainín E Humphreys Benjamin D BD
Nephron 20170609 4
End-stage renal disease (ESRD) is common, costly, and it results from progressive chronic kidney disease (CKD). ESRD claims many lives every year. It is increasingly recognized that episodes of acute kidney injury (AKI) predispose to the future development of CKD and ESRD. While our understanding of the pathophysiology of the AKI to CKD transition is improving, there are no validated therapeutic strategies to prevent this transition. In this review, we summarize the recent progress made in defin ...[more]
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