The Kv7 Channel and Cardiovascular Risk Factors.
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ABSTRACT:
SUBMITTER: Fosmo AL
PROVIDER: S-EPMC5723334 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Publications
The Kv7 Channel and Cardiovascular Risk Factors.
Fosmo Andreas L AL Skraastad Øyvind B ØB
Frontiers in cardiovascular medicine 20171205
Potassium channels play a pivotal role in the regulation of excitability in cells such as neurons, cardiac myocytes, and vascular smooth muscle cells. The KCNQ (Kv7) family of voltage-activated K<sup>+</sup> channels hyperpolarizes the cell and stabilizes the membrane potential. Here, we outline how Kv7 channel activity may contribute to the development of the cardiovascular risk factors such as hypertension, diabetes, and obesity. Questions and hypotheses regarding previous and future research ...[more]
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