Ontology highlight
ABSTRACT:
SUBMITTER: Kawagoe T
PROVIDER: S-EPMC5724408 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Kawagoe Tatsukata T Ota Masao M Meguro Akira A Takeuchi Masaki M Yamane Takahiro T Shimazaki Haruna H Takeuchi Masaru M Okada Eiichi E Teshigawara Takeshi T Mizuki Nobuhisa N
Clinical ophthalmology (Auckland, N.Z.) 20171207
<h4>Purpose</h4>The crystallin beta A4 (<i>CRYBA4</i>) gene variant, rs2009066, was previously reported to be associated with high myopia in a southern Chinese population. In the present study, we investigated whether <i>CRYBA4</i> variants were associated with high myopia in a Japanese population.<h4>Methods</h4>We recruited 1,063 Japanese patients with high myopia (spherical equivalent [SE] ≤-9.00 D in both eyes) and 1,009 healthy Japanese subjects (SE >-1.00 D). We genotyped rs2009066 and thr ...[more]