Functional and evolutionary analysis of Korean bob-tailed native dog using whole-genome sequencing data.

ABSTRACT: Rapid and cost effective production of large-scale genome data through next-generation sequencing has enabled population-level studies of various organisms to identify their genotypic differences and phenotypic consequences. This is also used to study indigenous animals with historical and economical values, although they are less studied than model organisms. The objective of this study was to perform functional and evolutionary analysis of Korean bob-tailed native dog Donggyeong with distinct tail and agility phenotype using whole-genome sequencing data by using population and comparative genomics approaches. Based on the uniqueness of non-synonymous single nucleotide polymorphisms obtained from next-generation sequencing data, Donggyeong dog-specific genes/proteins and their functions w

SUBMITTER: Lee D 

PROVIDER: S-EPMC5725459 | biostudies-literature | 2017 Dec

REPOSITORIES: biostudies-literature