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Electrophilic trifluoromethylselenolation of terminal alkynes with Se-(trifluoromethyl) 4-methylbenzenesulfonoselenoate.

ABSTRACT: Herein the nucleophilic addition of Se-(trifluoromethyl) 4-methylbenzenesulfonoselenoate, a stable and easy-to-handle reagent, to alkynes is described. This reaction provides trifluoromethylselenylated vinyl sulfones with good results and the method was extended also to higher fluorinated homologs. The obtained compounds are valuable building blocks for further syntheses of fluoroalkylselenolated molecules.

SUBMITTER: Ghiazza C

PROVIDER: S-EPMC5727788 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature

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Electrophilic trifluoromethylselenolation of terminal alkynes with <i>Se</i>-(trifluoromethyl) 4-methylbenzenesulfonoselenoate.

Ghiazza Clément C Tlili Anis A Billard Thierry T

Beilstein journal of organic chemistry 20171207

Herein the nucleophilic addition of <i>Se</i>-(trifluoromethyl) 4-methylbenzenesulfonoselenoate, a stable and easy-to-handle reagent, to alkynes is described. This reaction provides trifluoromethylselenylated vinyl sulfones with good results and the method was extended also to higher fluorinated homologs. The obtained compounds are valuable building blocks for further syntheses of fluoroalkylselenolated molecules. ...[more]

PMID: 29259673

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