Ontology highlight
ABSTRACT:
SUBMITTER: Manegold C
PROVIDER: S-EPMC5729303 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
Manegold Christian C Adjei Alex A Bussolino Federico F Cappuzzo Federico F Crino Lucio L Dziadziuszko Rafal R Ettinger David D Fennell Dean D Kerr Keith K Le Chevalier Thierry T Leighl Natasha N Papotti Mauro M Paz-Ares Luis L Pérol Maurice M Peters Solange S Pirker Robert R Quoix Elisabeth E Reck Martin M Smit Egbert E Vokes Everett E van Zandwijk Nico N Zhou Caicun C
ESMO open 20160101 6
Despite the efficacy of a number of first-line treatments, most patients with advanced-stage non-small cell lung cancer (NSCLC) experience disease progression that warrants further treatment. In this review, we examine the role of novel active agents for patients who progress after first-line therapy and who are not candidates for targeted therapies. More therapeutic options are needed for the management of patients with NSCLC after failure of first-line chemotherapy. A PubMed search was perform ...[more]