Ontology highlight
ABSTRACT:
SUBMITTER: Cywoniuk P
PROVIDER: S-EPMC5730568 | biostudies-literature | 2017 Dec
REPOSITORIES: biostudies-literature
Cywoniuk Piotr P Taylor Katarzyna K Sznajder Łukasz J ŁJ Sobczak Krzysztof K
Scientific reports 20171214 1
Alternative splicing is a complex process that provides a high diversity of proteins from a limited number of protein-coding genes. It is governed by multiple regulatory factors, including RNA-binding proteins (RBPs), that bind to specific RNA sequences embedded in a specific structure. The ability to predict RNA-binding regions recognized by RBPs using whole-transcriptome approaches can deliver a multitude of data, including false-positive hits. Therefore, validation of the global results is in ...[more]