Use of Comparative Genomics-Based Markers for Discrimination of Host Specificity in Fusarium oxysporum.

ABSTRACT: The polyphyletic nature of many formae speciales of Fusarium oxysporum prevents molecular identification of newly encountered strains based on conserved, vertically inherited genes. Alternative molecular detection methods that could replace labor- and time-intensive disease assays are therefore highly desired. Effectors are functional elements in the pathogen-host interaction and have been found to show very limited sequence diversity between strains of the same forma specialis, which makes them potential markers for host-specific pathogenicity. We therefore compared candidate effector genes extracted from 60 existing and 22 newly generated genome assemblies, specifically targeting strains affecting cucurbit plant species. Based on these candidate effector genes, a tot

SUBMITTER: van Dam P 

PROVIDER: S-EPMC5734036 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature