Ontology highlight
ABSTRACT: Objective
Chronic obstructive pulmonary disease (COPD) and benign prostatic hyperplasia (BPH) are common disorders in ageing male populations. Nevertheless, the relationship between the two diseases has rarely been explored. The objective of this study was to examine whether patients with COPD are at an increased risk of BPH.Design
Retrospective nationwide cohort study.Setting
Data retrieved from the Taiwan National Health Insurance Research Database.Participants
Overall, 19 959 male patients aged 40 years and over with newly diagnosed COPD between 2000 and 2006 were included as the COPD group, and 19 959 sex-matched and age-matched enrollees without COPD were included as the non-COPD group. Both groups were followed-up until the end of 2011.Outcome measures
A Cox proportional hazards regression model was used to compute the risk of BPH in patients with COPD compared with enrollees without COPD.Results
The overall incidence rate of BPH was 1.53 times higher in the COPD group than that in the non-COPD group (44.7 vs 25.7 per 1000 person-years, 95% CI 1.46 to 1.60) after adjusting for covariates. An additional stratified analysis revealed that this increased risk of BPH in patients with COPD remained significantly higher than that in enrollees without COPD in all men aged 40 years and over.Conclusion
After adjustment for covariates, male patients with COPD were found to be at a higher risk of BPH. We suggest that clinicians should be cautious about the increased risk of BPH in male patients with COPD.
SUBMITTER: Peng YH
PROVIDER: S-EPMC5734354 | biostudies-literature | 2017 Jun
REPOSITORIES: biostudies-literature
Peng Yi-Hao YH Huang Chien-Wen CW Liao Wei-Chih WC Chen Hsuan-Ju HJ Yin Ming-Chien MC Huang Yu-Ming YM Wu Trong-Neng TN Ho Wen-Chao WC
BMJ open 20170623 6
<h4>Objective</h4>Chronic obstructive pulmonary disease (COPD) and benign prostatic hyperplasia (BPH) are common disorders in ageing male populations. Nevertheless, the relationship between the two diseases has rarely been explored. The objective of this study was to examine whether patients with COPD are at an increased risk of BPH.<h4>Design</h4>Retrospective nationwide cohort study.<h4>Setting</h4>Data retrieved from the Taiwan National Health Insurance Research Database.<h4>Participants</h4> ...[more]