Ontology highlight
ABSTRACT:
SUBMITTER: Short SP
PROVIDER: S-EPMC5736147 | biostudies-literature | 2017 Jun
REPOSITORIES: biostudies-literature
Short Sarah P SP Short Sarah P SP Costacurta Patricia W PW Williams Christopher S CS
Current colorectal cancer reports 20170418 3
The three-dimensional (3D) structure of the intestine is a key determinant of differentiation and function; thus, preserving this architecture is an important consideration for studies of intestinal homeostasis and disease. Over the past decade, a number of systems for 3D intestinal organoid cultures have been developed and adapted to model a wide variety of biological phenomenon.<h4>Purpose of this review</h4>We discuss the current state of intestinal and colorectal cancer (CRC) 3D modeling, th ...[more]