Construction and analysis of circular RNA molecular regulatory networks in liver cancer.
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ABSTRACT:
SUBMITTER: Ren S
PROVIDER: S-EPMC5736333 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Publications
Construction and analysis of circular RNA molecular regulatory networks in liver cancer.
Ren Shuangchun S Xin Zhuoyuan Z Xu Yinyan Y Xu Jianting J Wang Guoqing G
Cell cycle (Georgetown, Tex.) 20171103 22
Liver cancer is the sixth most prevalent cancer, and the third most frequent cause of cancer-related deaths. Circular RNAs (circRNAs), a kind of special endogenous ncRNAs, have been coming back to the forefront of cancer genomics research. In this study, we used a systems biology approach to construct and analyze the circRNA molecular regulatory networks in the context of liver cancer. We detected a total of 127 differentially expressed circRNAs and 3,235 differentially expressed mRNAs. We selec ...[more]
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