Ontology highlight
ABSTRACT:
SUBMITTER: Zhou H
PROVIDER: S-EPMC5736595 | biostudies-literature | 2017 Dec
REPOSITORIES: biostudies-literature
Zhou Heng H Xiong Gui-Jing GJ Jing Liang L Song Ning-Ning NN Pu De-Lin DL Tang Xun X He Xiao-Bing XB Xu Fu-Qiang FQ Huang Jing-Fei JF Li Ling-Jiang LJ Richter-Levin Gal G Mao Rong-Rong RR Zhou Qi-Xin QX Ding Yu-Qiang YQ Xu Lin L
Nature communications 20171219 1
Encoding specificity theory predicts most effective recall by the original conditions at encoding, while generalization endows recall flexibly under circumstances which deviate from the originals. The CA1 regions have been implicated in memory and generalization but whether and which locally separated mechanisms are involved is not clear. We report here that fear memory is quickly formed, but generalization develops gradually over 24 h. Generalization but not fear memory is impaired by inhibitin ...[more]