Ontology highlight
ABSTRACT:
SUBMITTER: Yang N
PROVIDER: S-EPMC5736676 | biostudies-literature | 2018 Mar
REPOSITORIES: biostudies-literature
Yang Naery N Mun Yeung Chul YC Seong Chu Myong CM Huh Hee Jin HJ Huh Jungwon J
Annals of laboratory medicine 20180301 2
In multiple myeloma (MM), hyperdiploidy (HD) is known to impart longer overall survival. However, it is unclear whether coexistent HD ameliorates the adverse effects of known high-risk cytogenetics in MM patients. To address this issue, we investigated the clinicopathological characteristics of HD with high-risk cytogenetics in MM. Ninety-seven patients with MM were included in the study. For metaphase cytogenetics (MC), unstimulated cells from bone marrow aspirates were cultured for either 24 o ...[more]