Ontology highlight
ABSTRACT:
SUBMITTER: Lorenzo-Diaz F
PROVIDER: S-EPMC5737340 | biostudies-literature | 2017 Jul
REPOSITORIES: biostudies-literature
Lorenzo-Díaz Fabián F Fernández-López Cris C Lurz Rudi R Bravo Alicia A Espinosa Manuel M
Nucleic acids research 20170701 13
Horizontal gene transfer is a key process in the evolution of bacteria and also represents a source of genetic variation in eukaryotes. Among elements participating in gene transfer, thousands of small (<10 kb) mobile bacterial plasmids that replicate by the rolling circle mechanism represent a driving force in the spread of antibiotic resistances. In general, these plasmids are built as genetic modules that encode a replicase, an antibiotic-resistance determinant, and a relaxase that participat ...[more]