Ontology highlight
ABSTRACT:
SUBMITTER: Gonzalez GM
PROVIDER: S-EPMC5737377 | biostudies-literature | 2017 Oct
REPOSITORIES: biostudies-literature
Gonzalez Grecia M GM Durica-Mitic Svetlana S Hardwick Steven W SW Moncrieffe Martin C MC Resch Marcus M Neumann Piotr P Ficner Ralf R Görke Boris B Luisi Ben F BF
Nucleic acids research 20171001 18
In phylogenetically diverse bacteria, the conserved protein RapZ plays a central role in RNA-mediated regulation of amino-sugar metabolism. RapZ contributes to the control of glucosamine phosphate biogenesis by selectively presenting the regulatory small RNA GlmZ to the essential ribonuclease RNase E for inactivation. Here, we report the crystal structures of full length Escherichia coli RapZ at 3.40 Å and 3.25 Å, and its isolated C-terminal domain at 1.17 Å resolution. The structural data confi ...[more]