Ontology highlight
ABSTRACT:
SUBMITTER: Touma C
PROVIDER: S-EPMC5737504 | biostudies-literature | 2017 Aug
REPOSITORIES: biostudies-literature
Touma Christine C Adams Mark N MN Ashton Nicholas W NW Ashton Nicholas W NW Mizzi Michael M El-Kamand Serene S Richard Derek J DJ Cubeddu Liza L Gamsjaeger Roland R
Nucleic acids research 20170801 14
The maintenance of genome stability depends on the ability of the cell to repair DNA efficiently. Single-stranded DNA binding proteins (SSBs) play an important role in DNA processing events such as replication, recombination and repair. While the role of human single-stranded DNA binding protein 1 (hSSB1/NABP2/OBFC2B) in the repair of double-stranded breaks has been well established, we have recently shown that it is also essential for the base excision repair (BER) pathway following oxidative D ...[more]