Ontology highlight
ABSTRACT:
SUBMITTER: Smith SD
PROVIDER: S-EPMC5737730 | biostudies-literature | 2017 Oct
REPOSITORIES: biostudies-literature
Smith Sean D SD Kawash Joseph K JK Grigoriev Andrey A
GigaScience 20171001 10
Current human whole genome sequencing projects produce massive amounts of data, often creating significant computational challenges. Different approaches have been developed for each type of genome variant and method of its detection, necessitating users to run multiple algorithms to find variants. We present Genome Rearrangement OmniMapper (GROM), a novel comprehensive variant detection algorithm accepting aligned read files as input and finding SNVs, indels, structural variants (SVs), and copy ...[more]