Ontology highlight
ABSTRACT:
SUBMITTER: Jia J
PROVIDER: S-EPMC5738388 | biostudies-literature | 2017 Dec
REPOSITORIES: biostudies-literature
Jia Jia J King Jane E JE Goldrick Marie C MC Aldawood Esraa E Roberts Ian S IS
Scientific reports 20171220 1
In this study we characterise three tandem promoters (PR1-1, PR1-2 and PR1-3) within the PR1 regulatory region of the Escherichia coli kps capsule gene cluster. Transcription from promoter PR1-2 was dependent on the activity of the upstream promoter PR1-1, which activated PR1-2 via transcription coupled DNA supercoiling. During growth at 37 °C a temporal pattern of transcription from all three promoters was observed with maximum transcriptional activity evident during mid-exponential phase follo ...[more]