Ontology highlight
ABSTRACT:
SUBMITTER: Gasparotto AS
PROVIDER: S-EPMC5738613 | biostudies-literature | 2017 Oct-Dec
REPOSITORIES: biostudies-literature
Gasparotto Aline Simas AS Borges Diego Olschowsky DO Zandoná Marília Remuzzi MR Ramos Mauricio Jacques MJ Meihnardt Nelson Guardiola NG Mattevi Vanessa S VS
Genetics and molecular biology 20171023 4
Our aim was to investigate if single nucleotide polymorphisms (SNPs) located in the 5' regions of leptin (LEP, -2548 G > A, rs7799039), resistin (RETN, -420 C > G, rs1862513) and adiponectin (ADIPOQ, -11391 G > A, rs17300539 and -11377 C > G, rs266729) genes were related to changes in body mass index (BMI) and metabolic variables after bariatric surgery in 60 extremely obese individuals. At baseline, ADIPOQ -11391 A-allele carriers showed higher plasma adiponectin and lower total cholesterol lev ...[more]