Ontology highlight
ABSTRACT:
SUBMITTER: Liu X
PROVIDER: S-EPMC5739698 | biostudies-literature | 2017 Dec
REPOSITORIES: biostudies-literature
Liu Xingjian X Li Yinü Y Hu Xiaoyuan X Yi Yongzhu Y Zhang Zhifang Z
Oncotarget 20171120 62
The baculovirus <i>Autographa californica</i> multicapsid nucleopolyhedrovirus (<i>Ac</i>MNPV) has been investigated as a possible tool for gene therapy, but its inhibition by complement proteins in human serum limits its applicability. Here, we used the baculovirus <i>Bombyx mori</i> nucleopolyhedrovirus (<i>Bm</i>NPV) to construct a gene delivery vector in which a reporter gene is driven by a cytomegalovirus IE promoter. Enhanced green fluorescent protein (EGFP) and luciferase reporter genes w ...[more]