Ontology highlight
ABSTRACT:
SUBMITTER: Bouguenina H
PROVIDER: S-EPMC5740655 | biostudies-literature | 2017 Dec
REPOSITORIES: biostudies-literature
Bouguenina Habib H Salaun Danièle D Mangon Aurélie A Muller Leslie L Baudelet Emilie E Camoin Luc L Tachibana Taro T Cianférani Sarah S Audebert Stéphane S Verdier-Pinard Pascal P Badache Ali A
Proceedings of the National Academy of Sciences of the United States of America 20171121 50
Control of microtubule dynamics underlies several fundamental processes such as cell polarity, cell division, and cell motility. To gain insights into the mechanisms that control microtubule dynamics during cell motility, we investigated the interactome of the microtubule plus-end-binding protein end-binding 1 (EB1). Via molecular mapping and cross-linking mass spectrometry we identified and characterized a large complex associating a specific isoform of myomegalin termed "SMYLE" (for short myom ...[more]