Design and Implementation of a Prospective Adult Congenital Heart Disease Biobank.

ABSTRACT:

Background

Adults with congenital heart disease (ACHD) comprise a growing, increasingly complex population. The Boston Adult Congenital Heart Disease Biobank is a program for the collection and storage of biospecimens to provide a sustainable resource for scientific biomarker investigation in ACHD.

Methods

We describe a protocol to collect, process, and store biospecimens for ACHD or associated diagnoses developed based on existing literature and consultation with cardiovascular biomarker epidemiologists. The protocol involves collecting urine and ∼48.5 mL of blood. A subset of the blood and urine undergoes immediate clinically relevant testing. The remaining biospecimens are processed soon after collection and stored at -80°C as aliquots of ethylenediaminetetraacetic acid (

SUBMITTER: Opotowsky AR 

PROVIDER: S-EPMC5742285 | biostudies-literature | 2016 Nov

REPOSITORIES: biostudies-literature