Ontology highlight
ABSTRACT:
SUBMITTER: Hsu FS
PROVIDER: S-EPMC5742464 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Journal of immunology research 20171210
Few effective treatment options are available for patients with advanced or metastatic urothelial carcinoma (UC) after unsuccessful first-line platinum-based chemotherapy. To date, immune checkpoint inhibitors are novel therapeutic agents for UC treatment. From May 2016 to May 2017, five anti-PD-1/PD-L1 monoclonal antibodies received accelerated or regular approval from the US Food and Drug Administration (FDA) for the treatment of patients with locally advanced or metastatic UC. The present com ...[more]