Dataset Information
Ambient Temperature and Stillbirth: A Multi-Center Retrospective Cohort Study.
Ontology highlight
ABSTRACT: Background
Climate change is expected to have adverse health effects, but the association between extreme ambient temperatures and stillbirth is unclear.Objectives
We investigated acute and chronic associations between extreme ambient temperatures and stillbirth risk, and estimated the attributable risk associated with local temperature extremes in the United States.Methods
We linked 223,375 singleton births ?23?weeks of gestation (2002–2008) from 12 U.S. sites to local temperature. Chronic exposure to hot (>90th?percentile), cold (<10th?percentile), or mild (10th–90th?percentile) temperatures was defined using window- and site-specific temperature distributions for three-months preconception, first and second trimester, and whole-pregnancy averages. For acute exposure, average temperature for the week preceding delivery was compared to two alternative control weeks in a case-crossover analysis.Results
In comparison with mild, whole-pregnancy exposure to cold [adjusted odds ratio (aOR) = 4.75; 95% confidence interval (CI): 3.95, 5.71] and hot (aOR = 3.71; 95% CI: 3.07, 4.47) were associated with stillbirth risk, and preconception and first and second trimester exposures were not. Approximately 17–19% of stillbirth cases were potentially attributable to chronic whole-pregnancy exposures to local temperature extremes. This is equivalent to ?1,116?cold-related and ?1,019?hot-related excess cases in the United States annually. In the case-crossover analysis, a 1°C increase during the week preceding delivery was associated with a 6%?(3–9%) increase in stillbirth risk during the warm season (May–September). This incidence translates to ?4?(2–6) additional stillbirths per 10,000 births for each 1°C increase.Conclusions
Extremes of local ambient temperature may have chronic and acute effects on stillbirth risk, even in temperate zones. Temperature-related effects on pregnancy outcomes merit additional investigation. https://doi.org/10.1289/EHP945.
SUBMITTER: Ha S
PROVIDER: S-EPMC5743476 | biostudies-literature | 2017 Jun
REPOSITORIES: biostudies-literature
Publications
Ambient Temperature and Stillbirth: A Multi-Center Retrospective Cohort Study.
Environmental health perspectives 20170622 6
<h4>Background</h4>Climate change is expected to have adverse health effects, but the association between extreme ambient temperatures and stillbirth is unclear.<h4>Objectives</h4>We investigated acute and chronic associations between extreme ambient temperatures and stillbirth risk, and estimated the attributable risk associated with local temperature extremes in the United States.<h4>Methods</h4>We linked 223,375 singleton births ≥23 weeks of gestation (2002–2008) from 12 U.S. sites to local t ...[more]
