Ontology highlight
ABSTRACT:
SUBMITTER: Lee DH
PROVIDER: S-EPMC5747077 | biostudies-literature | 2017 Dec
REPOSITORIES: biostudies-literature
Lee Dong-Hun DH Kim Ah-Ra AR Lee Su-Hwa SH Quan Fu-Shi FS
Parasites & vectors 20171229 1
<h4>Background</h4>Human clonorchiasis, caused by the infection of Clonorchis sinensis, is one of the major health problems in Southeast Asia. However, vaccine efficacy against C. sinensis infection remains largely unknown.<h4>Methods</h4>In this study, for the first time, we generated virus-like particles (VLPs) vaccine containing the C. sinensis tegumental protein 22.3 kDa (CsTP 22.3) and the influenza matrix protein (M1) as a core protein, and investigated the vaccine efficacy in Sprague-Dawl ...[more]