Mining Filarial Genomes for Diagnostic and Therapeutic Targets.
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ABSTRACT:
SUBMITTER: Bennuru S
PROVIDER: S-EPMC5748246 | biostudies-literature | 2018 Jan
REPOSITORIES: biostudies-literature
Publications
Mining Filarial Genomes for Diagnostic and Therapeutic Targets.
Bennuru Sasisekhar S O'Connell Elise M EM Drame Papa M PM Nutman Thomas B TB
Trends in parasitology 20171012 1
Filarial infections of humans cause some of the most important neglected tropical diseases. The global efforts for eliminating filarial infections by mass drug administration programs may require additional tools (safe macrofilaricidal drugs, vaccines, and diagnostic biomarkers). The accurate and sensitive detection of viable parasites is essential for diagnosis and for surveillance programs. Current community-wide treatment modalities do not kill the adult filarial worms effectively; hence, the ...[more]
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