Ontology highlight
ABSTRACT:
SUBMITTER: Chook JB
PROVIDER: S-EPMC5749291 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Chook Jack Bee JB Ngeow Yun Fong YF Tee Kok Keng KK Peh Suat Cheng SC Mohamed Rosmawati R
Journal of pathogens 20171219
Fulminant hepatitis (FH) is a life-threatening liver disease characterised by intense immune attack and massive liver cell death. The common precore stop codon mutation of hepatitis B virus (HBV), A1896, is frequently associated with FH, but lacks specificity. This study attempts to uncover all possible viral nucleotides that are specifically associated with FH through a compiled sequence analysis of FH and non-FH cases from acute infection. We retrieved 67 FH and 280 acute non-FH cases of hepat ...[more]