Ontology highlight
ABSTRACT:
SUBMITTER: Pearl MH
PROVIDER: S-EPMC5750071 | biostudies-literature | 2018 Jan
REPOSITORIES: biostudies-literature
Pearl Meghan H MH Zhang Qiuheng Q Palma Diaz Miguel Fernando MF Grotts Jonathan J Rossetti Maura M Elashoff David D Gjertson David W DW Weng Patricia P Reed Elaine F EF Tsai Chambers Eileen E
Kidney international 20170918 1
Angiotensin II type 1 receptor (AT1R) antibody has been linked to poor allograft outcomes in adult kidney transplantation. However, its clinical consequences in children are unknown. To study this, we examined the relationship of AT1R antibody with clinical outcomes, biopsy findings, inflammatory cytokines, and HLA donor-specific antibodies (DSA) in a cohort of pediatric renal transplant recipients. Sixty-five patients were longitudinally monitored for AT1R antibody, HLA DSA, IL-8, TNF-α, IL-1β, ...[more]