Ontology highlight
ABSTRACT:
SUBMITTER: Dagonnier M
PROVIDER: S-EPMC5751906 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Dagonnier Marie M Cooke Ira Robin IR Faou Pierre P Sidon Tara Kate TK Dewey Helen Margaret HM Donnan Geoffrey Alan GA Howells David William DW
Biomarker insights 20171220
Application of acute therapies such as thrombolysis for ischaemic stroke (IS) is constrained because of diagnostic uncertainty and the dynamic nature of stroke biology. To investigate changes in blood proteins after stroke and as a result of thrombolysis treatment we performed label-free quantitative proteomics on serum samples using high-resolution mass spectrometry and long high-performance liquid chromatography gradient (5 hours) combined with a 50-cm column to optimise the peptide separation ...[more]